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Other scientists have not specifically mentioned metformin but in his 2005 book on mitochondria, Nick Lane suggests that if we live longer to rid ourselves of diseases of old age we need more mitochondria and perhaps a more refined free-radical detection system (357)

10.1001/jama.2009.1346 238

Contribution of Ser463 residue to the enzymatic and autoprocessing activities of Escherichia coli gamma-glutamyltranspeptidase

Effects of curcumin on mitochondria in neurodegenerative diseases

Acute ELAM treatment significantly increased uptake of [ 3 H]ADP by aged heart isolated mitochondria, specifically at the concentrations with the highest decrease in aged control samples (1030 M ADP) (Fig